These databases contain human cell line STR profiles and are essential resources when authenticating human cell lines. Source. The five major dataset types are Copy Number, mRNA expression (Affy), RPPA, RRBS, and mRNA expression (RNAseq). The 'Excel' button is not availible in Safari. |
Database of Cross-Contaminated or Misidentified Cell Lines compiled by the International Cell Line Authentication Committee (ICLAC). Selecting a new lineage from the menu will replace the currently displayed bubble map. Treatment . (LIMORE) composed of 81 human liver cancer cell models, including 50 newly generated models.
To view methylation, select one, or multiple, lineages from the menu. Please stay tuned, Genomics of Drug Sensitivity in Cancer Project (GDSC), Cancer Therapeutics Response Portal (CTRP), Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Key Lab of Computational Biology, PICB, SIBS, CAS. Change. Prot. You may not download or use the Database, or any portion thereof, for any use not expressly authorized hereunder without prior written permission from Broad. It attempts to describe all cell lines used in biomedical research.
COSMIC is divided into several distinct projects, each presenting a separate dataset or view of our data: COSMIC. Gene expression data can be visualized as box plots or compared to other expression values in scatter plots. P. Romano, A. Manniello, O. Aresu, M. Armento, M. Cesaro, B. Parodi. Aided by simple prompts, users can input their own cell line STR data to retrieve best matches with authenticated cell lines listed on the database. The file will be tab delimited. *, Li, H., Li, C., Zhang, Z., Chen, X., Cen, J., Meng, Z., Zhang, H., Li, Y., and Hui, L. (2016) Hepatocellular carcinoma cell lines retain the genomic and transcriptomic landscapes of primary human cancers. The X axis shows distributions of the original gene, while the Y axis shows distributions of the new selected gene. PMID: 18927105, Identification (name, typology, karyology, morphology,...), Origin (tissue, species, tumour, pathology,...), Properties (specific functions, products and applications), Retrieval sources (bibliographic references, catalogue codes,...), Extensively characterized cell lines (immunological profile, cytogenetic analysis...). (one of the top 100 read SR articles in 2016). Mousing over a specific bubble gives more specific information, such as coverage and methylation. You agree to preserve, at all times, the confidentiality of Data pertaining to identifiable Data Subjects. You will also declare in any such work that those who carried out the original analysis and collection of the Data bear no responsibility for the further analysis or interpretation of it. The database is administered by the US National Library of Medicine, National Institutes of Health. The amelogenin gene is a genetic marker used for gender determination and is not comprised of STR units. To zoom, click and drag over the area of the graph you want to zoom in on.
Animal cell lines: 1380 (Species: 204) ISO 17025
ATCC cultures are critical to the discovery, invention, and development of new, improved and emerging scientific advances. The search is auto completable. between genetic alterations and drug responses would facilitate precision treatment for liver cancers. The cell line name and lineage are listed at the top of the cell line page. The Cell-culture Database can be used for: a. - of which, transformed: 123 Interrogation of the pharmacogenomic landscape from a You agree to notify Broad of any errors detected in the Data. Bubble Size represents coverage, and bubble color represents methylation, with warmer colors being more methylated. FAQ The gene name, description and Entrez ID are listed at the top of the gene page. to conduct a detailed genetic and pharmacologic characterization of a large panel of human cancer models, to develop integrated computational analyses that link distinct pharmacologic vulnerabilities to genomic patterns and to translate cell line integrative genomics into cancer patient stratification.
Tissues - Tumors - Type.
The first visualization displays the distribution of the genes expression data for a given dataset. Allele 2. I tried hyperCLDB but still a lot of cell lines are not covered in there.
An email will be sent to you with instructions. You agree to use the acknowledgement wording provided for the relevant Data in its publication. The information and materials ("Data") made available on this web site (www.broadinstitute.org/ccle), including the database of cancer cell lines genomic profiles and mutations (referred to collectively herein as the "Database") are made available to you (and your employing entity, where the download or use is within the scope of your employment by such entity- collectively "You") solely for internal research purposes. Morevoer, predictive biomarkers and models were developed to facilitate the Please insert cell line name: Or choose one of the following: ... HLA-Data.
The NCBI BioSample database archives STR profiles and descriptions for several thousand cell lines, as provided by cell line repositories. Database of Cross-Contaminated or Misidentified Cell Lines compiled by the International Cell Line Authentication Committee (ICLAC). Subtype. Position (hg19) Type. However, if you would like to, you can change your cookie settings at anytime. Cell Lines Project. to prevalent alterations, in liver cancers. - of which, transformed: 277, If you want to cite CLDB and HyperCLDB, please use the following reference: The X axis displays the position of the Methylation data.
The search offers you access to our complete catalogue of DSMZ human and animal cell lines. The Cellosaurus is a knowledge resource on cell lines. Gene Methylation can also be visualized through a bubble map. | ... Leibniz Institute DSMZ operates a user-friendly interface to query its database of STR profiles, brought together in collaboration with cell banks ATCC, JCRB, and RIKEN as a human cell line cross-contamination initiative. Total cell lines: 6643 (includes lines not admitted to distribution) You are using this Database at Your own risk, and You hereby agree to hold Broad and its contributors and their trustees, directors, officers, employees, and affiliated investigators harmless for any third party claims which may arise from Your download or use of the Database or any portion thereof. Question: Cell lines database. Transcript. The highest average distribution is on the left and is colored red. Nucleic Acids Research 2009 37(Database issue):D925-D932. ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, NONINFRINGEMENT, OR THE ABSENCE OF LATENT OR OTHER DEFECTS ARE DISCLAIMED. For each cell line (currently ~120,000) the Cellosaurus provides a wealth of information. kzkedzierska • 160 wrote: Hi guys, does anyone know is there a way to access ATCC database to get all the info about the cell lines, like tissue of origin, species etc?
Or is there another db that will cover all that? University of Oxford. Search - Web Sites In particular, You shall undertake not to use, or attempt to use the Data to deliberately compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy. Ethical Standards for Obtaining Human Materials, Nucleic Acids, Proteins and Cell Extracts. © 2020 ATCC. The first dropdown selects for the X Axis, while the second selects for the Y Axis. The number next to the lineage name indicates how many cell lines are in the lineage.
ATCC STR profile database (search and compare STR profiles, login required) Cellosaurus – a knowledge resource on cell lines (search cell line name or description) CLASTR: the Cellosaurus STR similarity search tool (search and compare STR profiles) CLIMA database (search and compare STR profiles, version 2.1) DS…
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